Parietal nodular lesion on the scalp: probable renal cell carcinoma metastasis - a case report
DOI:
https://doi.org/10.37085/jmmv4.n2.2022.pp.23-28Palavras-chave:
Renal metastasis, Parietal lesion, Scalp, Renal cell carcinomaResumo
Among the renal lesions described, renal cell carcinoma (RCC) is the primary renal neoplastic tumor reaching males in a proportion two times higher than females and characterizing about 2% of the carcinomas of the adult population. Although the treatment of this type of cancer has evolved in recent years, the management of patients with metastatic conditions remains challenging, with possible spreads to the lungs and bones. Vascular metastasis of RCC to the skin, especially the scalp, is a rare condition with few reports described in the literature. The diagnosis of this lesion should consider the patient's clinic, especially in cases with a previous history of renal carcinoma, and maybe a differential diagnosis for vascular lesions. Although the treatment is surgical, there may be an association with possible adjuvant treatments.
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Rini BI, Campbell SC and Escudier B. Renal cell carcinoma. Lancet 2009;373(9669):1119-1132 Doi:10.1016/s0140-6736(09)60229-4
Gupta K, Miller JD, Li JZ, Russell MW and Charbonneau C. Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review. Cancer Treat Rev 2008;34(3):193-205 Doi:10.1016/j.ctrv.2007.12.001
Lam JS, Leppert JT, Belldegrun AS and Figlin RA. Novel approaches in the therapy of metastatic renal cell carcinoma. World J Urol 2005;23(3):202-212 Doi:10.1007/s00345-004-0466-0
Paula TA, Silva PS and Berriel LG. Renal cell carcinoma with cutaneous metastasis: case report. J Bras Nefrol 2010;32(2):213-215
Chan TY. World Health Organization classification of tumours: Pathology & genetics of tumours of the urinary system and male genital organs. Urology 2005;65:214-215 Doi:10.1016/j.urology.2004.09.048
Qi X, Li Q, Che X, Wang Q and Wu G. The Uniqueness of Clear Cell Renal Cell Carcinoma: Summary of the Process and Abnormality of Glucose Metabolism and Lipid Metabolism in ccRCC. Front Oncol 2021;11:727778 Doi:10.3389/fonc.2021.727778
Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127(12):2893-2917 Doi:10.1002/ijc.25516
Zagoria RJ. Imaging of small renal masses: a medical success story. AJR Am J Roentgenol 2000;175(4):945-955 Doi:10.2214/ajr.175.4.1750945
Lipworth L, Tarone RE and McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol 2006;176(6 Pt 1):2353-2358 Doi:10.1016/j.juro.2006.07.130
Abouassaly R, Lane BR and Novick AC. Active surveillance of renal masses in elderly patients. J Urol 2008;180(2):505-508; discussion 508-509 Doi:10.1016/j.juro.2008.04.033
El Dib R, Touma NJ and Kapoor A. Cryoablation vs radiofrequency ablation for the treatment of renal cell carcinoma: a meta-analysis of case series studies. BJU Int 2012;110(4):510-516 Doi:10.1111/j.1464-410X.2011.10885.x
Ljungberg B, Bensalah K, Canfield S, Dabestani S, Hofmann F, Hora M, . . . Bex A. EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol 2015;67(5):913-924 Doi:10.1016/j.eururo.2015.01.005
Bujons A, Pascual X, Martínez R, Rodríguez O, Palou J and Villavicencio H. Cutaneous metastases in renal cell carcinoma. Urol Int 2008;80(1):111-112 Doi:10.1159/000111742
Bianchi M, Sun M, Jeldres C, Shariat SF, Trinh QD, Briganti A, . . . Karakiewicz PI. Distribution of metastatic sites in renal cell carcinoma: a population-based analysis. Ann Oncol 2012;23(4):973-980 Doi:10.1093/annonc/mdr362
Alcaraz I, Cerroni L, Rütten A, Kutzner H and Requena L. Cutaneous metastases from internal malignancies: a clinicopathologic and immunohistochemical review. Am J Dermatopathol 2012;34(4):347-393 Doi:10.1097/DAD.0b013e31823069cf
Arrabal-Polo MA, Arias-Santiago SA, Aneiros-Fernandez J, Burkhardt-Perez P, Arrabal- Martin M and Naranjo-Sintes R. Cutaneous metastases in renal cell carcinoma: a case report. Cases J 2009;2:7948 Doi:10.4076/1757-1626-2-7948
Barbagelata López A, Ruibal Moldes M, Blanco Díez A, Fernández Rosado E, Ponce Díaz-Reixa JL, Novas Castro S, . . . González Martín M. Cutaneous metastasis of a renal carcinoma: case report and review. Arch Esp Urol 2005;58(3):247-250 Doi:10.4321/s0004-06142005000300011
Dorairajan LN, Hemal AK, Aron M, Rajeev TP, Nair M, Seth A, . . . Gupta NP. Cutaneous metastases in renal cell carcinoma. Urol Int 1999;63(3):164-167 Doi:10.1159/000030440
Haruki T, Takahashi S, Morohashi M, Maruyama T and Ida M. Cutaneous metastasis of renal cell carcinoma: an electron microscopic study. J Dermatol 1991;18(4):218-224 Doi:10.1111/j.1346-8138.1991.tb03071.x
Williams JC and Heaney JA. Metastatic renal cell carcinoma presenting as a skin nodule: case report and review of the literature. J Urol 1994;152(6 Pt 1):2094-2095 Doi:10.1016/s0022-5347(17)32319-4
Katta R. What's causing these scalp nodules? Cutaneous metastasis. Postgrad Med 2000;108(4):115-116 Doi:10.3810/pgm.2000.09.15.1246
Snow S, Madjar D, Reizner G, Mac KE and Bentz M. Renal cell carcinoma metastatic to the scalp: case report and review of the literature. Dermatol Surg 2001;27(2):192-194 Doi:10.1046/j.1524-4725.2001.00115.x
Pan D, Niall O, Sharma H and Gya D. Isolated scalp nodule in patient with undiagnosed RCC. ScientificWorldJournal 2006;6:2430-2432 Doi:10.1100/tsw.2007.377
Jin WW, Chung JM, Jung KE, Park JW and Kim MH. A Case of Metastatic Renal Cell Carcinoma Mimicking Granuloma Pyogenicum. Ann Dermatol 2008;20(4):263-266 Doi:10.5021/ad.2008.20.4.263
Rekhi B, Kumar R, Menon S, Medhi S and Desai SB. Calvarial metastasis of a renal cell carcinoma, mimicking a primary alveolar soft part sarcoma, in a young girl-a rare case report. Pathol Oncol Res 2009;15(1):137-141 Doi:10.1007/s12253-008-9097-x
Song IC, Lim JS, Yun HJ, Kim S, Kang DY and Lee HJ. Biochemical and pathological response of prostate cancer in a patient with metastatic renal cell carcinoma on sunitinib treatment. Jpn J Clin Oncol 2009;39(12):833-836 Doi:10.1093/jjco/hyp110
Johnson RP, Krauland K, Owens NM and Peckham S. Renal medullary carcinoma metastatic to the scalp. Am J Dermatopathol 2011;33(1):e11-13 Doi:10.1097/DAD.0b013e3181e4b4eb
Matias M, Casa-Nova M, Borges-Costa J and Ribeiro L. Unusual head metastasis of kidney cancer. BMJ Case Rep 2013;2013:bcr2013200004 Doi:10.1136/bcr-2013-200004
Abbasi F, Alizadeh M, Noroozinia F and Moradi A. Cutaneous metastasis of bilateral renal cell carcinoma. J Pak Med Assoc 2013;63(1):111-113
Anzalone CL, Cohen PR, Migden MR and Tannir NM. Mohs surgery in metastatic cancer: renal cell carcinoma solitary cutaneous metastasis and visceral tumor metastases to skin treated with microscopically controlled surgical excision. Int J Dermatol 2013;52(7):856-861 Doi:10.1111/ijd.12021
Errami M, Margulis V and Huerta S. Renal Cell Carcinoma Metastatic to the Scalp. Rare Tumors 2016;8(4):6400 Doi:10.4081/rt.2016.6400
Selvi F, Faquin WC, Michaelson MD and August M. Three Synchronous Atypical Metastases of Clear Cell Renal Carcinoma to the Maxillary Gingiva, Scalp and the Distal Phalanx of the Fifth Digit: A Case Report. J Oral Maxillofac Surg 2016;74(6):1281-1289 Doi:10.1016/j.joms.2016.01.054
McAndrew R and Ghasri P. Firm pink nodule on the scalp. Cutis 2016;98(6):376;383;384
Tjarks BJ and Ferringer TC. Red-blue nodule on the scalp. Cutis 2017;99(1):15;25;26
Georgy JT, Mathuram AJ, George AA and Chandramohan J. Renal cell carcinoma presenting as a cutaneous horn and nodules on the gingiva and scalp. BMJ Case Rep 2017;2017:bcr2017220913 Doi:10.1136/bcr-2017-220913
Badri M, Gader G, Bahri K and Zammel I. Skull metastasis revealing a renal tumor: A case report and review of the literature. Int J Surg Case Rep 2018;43:56-60 Doi:10.1016/j.ijscr.2018.01.025
Zhou MH, Dunn GP, Osbun JW, Cross DT, 3rd, Moran CJ, Dacey RG, Jr. and Kansagra AP. Direct puncture Onyx embolization of a large calvarial metastasis with intracranial extension: Case report. Interv Neuroradiol 2018;24(2):220-224 Doi:10.1177/1591019917740353
Kishore M, Chauhan DS and Dogra S. Unusual presentation of renal cell carcinoma: A rare case report. J Lab Physicians 2018;10(2):241-244 Doi:10.4103/jlp.Jlp_153_17
Ferhatoglu MF, Senol K and Filiz AI. Skin Metastasis of Renal Cell Carcinoma: A Case Report. Cureus 2018;10(11):e3614 Doi:10.7759/cureus.3614
Mann J, Wernham A, Kulkarni K and Varma S. An unexpected lesion on the scalp. Clin Exp Dermatol 2020;45(7):922-924 Doi:10.1111/ced.14268
Krogerus C, Svenning M, Pilt AP and Trøstrup H. Renal cell carcinoma presenting as a tumor on the scalp: A case report. Int J Surg Case Rep 2020;76:56-59 Doi:10.1016/j.ijscr.2020.09.122
Balawender K, Przybyła R, Orkisz S, Wawrzyniak A, Boroñ D and Grabarek BO. Cutaneous metastasis as the first sign of renal cell carcinoma - crossroad between literature analysis and own observations. Postepy Dermatol Alergol 2022;39(3):553-558 Doi:10.5114/ada.2021.108275
Leve PP, Felício J, Carneiro R and Zagalo C. Recurrent renal cell carcinoma presenting as a cutaneous metastasis: A case report and review of the literature. Urol Ann 2021;13(2):174-176 Doi:10.4103/ua.Ua_2_20
Singla A, Sharma U, Makkar A, Masood PF, Goel HK, Sood R, . . . Singh R. Rare metastatic sites of renal cell carcinoma: a case series. Pan Afr Med J 2022;42:26 Doi:10.11604/pamj.2022.42.26.33578
Jindal T, Sinha RK, Mukherjee S and Karmakar D. Calvarial and cutaneous metastasis as the primary presentation of a renal cell carcinoma. BMJ Case Rep 2014;2014:bcr2013202830 Doi:10.1136/bcr-2013-202830
Harrison MR, Costello BA, Bhavsar NA, Vaishampayan U, Pal SK, Zakharia Y, . . . George DJ. Active surveillance of metastatic renal cell carcinoma: Results from a prospective observational study (MaRCC). Cancer 2021;127(13):2204-2212 Doi:10.1002/cncr.33494
Koga S, Tsuda S, Nishikido M, Matsuya F, Saito Y and Kanetake H. Renal cell carcinoma metastatic to the skin. Anticancer Res 2000;20(3b):1939-1940
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